Abstract Background Small supernumerary marker chromosomes (sSMC) are additional centric chromosome fragments too small to be identified by banding cytogenetics alone. A sSMC can originate from any chromosome and it is estimated that 70% of sSMC are de novo. while 30% are inherited. Cases of sSMC derived from chromosome 5 (sSMC5) are rare. https://pipingrockers.shop/product-category/clear-sinus/